Abnova

CHN1 Monoclonal Antibody (3A3)

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CHN1 Antibody in Western Blot (WB) — CHN1 monoclonal antibody (M03), clone 3A3. Western Blot analysis of CHN1 expression in NIH/3T3(Cat # L018V1).

CHN1 Antibody in ELISA (ELISA) — Detection limit for recombinant GST tagged CHN1 is approximately 0.1 ng/mL as a capture antibody.

Product Details

H00001123-M03

Applications	Tested Dilution	Publications
Western Blot (WB)	1-5 µg/mL	-
ELISA (ELISA)	0.1 ng/mL	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Host/Isotype	Mouse / IgG2a, kappa
Class	Monoclonal
Type	Antibody
Clone	3A3
Immunogen	CHN1 (AAH11393, 91 a.a. approximately 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	See Label
Purification	Affinity chromatography
Storage buffer	PBS, pH 7.4
Contains	no preservative
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Sequence of this protein is as follows: QTRNFRLYYD GKHFVGEKRF ESIHDLVTDG LITLYIETKA AEYIAKMTIN PIYEHVGYTT LNREPAYKKH MPVLKETHDE RDSTGQDGVS EKRLTSLVRR ATLKENEQIP

Target Information

GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: A-chimaerin; a2-chimaerin; Alpha-chimerin; alpha1 chimaerin; alpha2 chimaerin; alpha3-chimerin; chimaerin; chimaerin 1; chimerin (chimaerin) 1; N-chimaerin; N-chimerin; NC; Rho GTPase-activating protein 2

Gene Aliases: 0610007I19Rik; 0710001E19Rik; 1700112L09Rik; 2900046J01Rik; AI413815; ARHGAP2; CHN; CHN1; DURS2; NC; RHOGAP2

UniProt ID: (Human) P15882, (Rat) P30337, (Mouse) Q91V57

Entrez Gene ID: (Human) 1123, (Rat) 84030, (Mouse) 108699

Function(s)

motor neuron axon guidance positive regulation of signal transduction intracellular signal transduction positive regulation of GTPase activity ephrin receptor signaling pathway regulation of axonogenesis regulation of small GTPase mediated signal transduction signal transduction nervous system development regulation of GTPase activity

Process(es)

SH3/SH2 adaptor activity GTPase activator activity protein binding metal ion binding ephrin receptor binding phorbol ester receptor activity