|Tested species reactivity||Bacteria|
|Host / Isotype||Mouse / IgM|
|Immunogen||Vibrio cholerae extract|
|Purification||Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Cholera toxin (CT) acts by transfer of ADP-ribose from intracellular NAD to the alpha chain of a trimeric G protein that functions to stimulate adenylate cyclase resulting in the increase of host cell cAMP. CT binds via the beta subunits to the GM1 ganglioside. Gangliosides are glycolipids that also contain oligosaccharides with one or more sialic acid residues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.