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Sequence of this protein is as follows: MPVYESVFME DGETTRKIAL ETERPPQVEV HVWTIRKGIL QHFHIEKISK RMFEELPHFK LVTRTTLSQW KIFTEGEAQI SQMCSSRVCR TELEDLVKVL YLERSEKGHC
CHRDL1 is an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chordin-like 1; Chordin-like protein 1; neuralin 1; Neuralin-1; Neurogenesin-1; Ventroptin
Gene Aliases: CHL; CHRDL1; dA141H5.1; MGC1; MGCN; NRLN1; VOPT
UniProt ID: (Human) Q9BU40
Entrez Gene ID: (Human) 91851
Molecular Function:
cell adhesion molecule
extracellular matrix glycoprotein
extracellular matrix protein
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