|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||An C-terminal synthetic peptide made to the human ChREBP protein sequence (between residues 800-852).|
|Purification||Antigen affinity chromatography|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
|ChIP assay (ChIP)||1:10-1:500|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|ChIP assay (ChIP)||See 1 publications below|
The target sequence has 83% sequence homology with mouse ChREBP.
ChREBP is a transcription factor involved in activating genes that encode enzymes of fatty acid biosynthesis in liver and adipose. This protein may have relevance to lipid metabolism, obesity, and type II diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Induction of the ChREBPß Isoform Is Essential for Glucose-Stimulated ß-Cell Proliferation.
PA5-22924 was used in ChIP assay to study the relationship between ChREBPbeta and glucose in beta cells
|Zhang P,Kumar A,Katz LS,Li L,Paulynice M,Herman MA,Scott DK||Diabetes (64:4158)||2015|