MA5-31689 has been tested in indirect ELISA.
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
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Protein Aliases: acetylcholine receptor; acetylcholine receptor, nicotinic, alpha 6 (neuronal); cholinergic receptor; cholinergic receptor, nicotinic alpha 6; cholinergic receptor, nicotinic, alpha 6 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 6; Neuronal acetylcholine receptor subunit alpha-6
Gene Aliases: CHNRA6; CHRNA6
UniProt ID: (Human) Q15825
Entrez Gene ID: (Human) 8973
Molecular Function: ligand-gated ion channel