Immunogen sequence: NYVLQLAGVG SYLKFPTYAK STRTTDEMTT EFFQNISSEH QTQLYEVYKL DFLMFNYSVP SYLK
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%.
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6- di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C4S-1; C4ST-1; C4ST1; Carbohydrate sulfotransferase 11; Chondroitin 4-O-sulfotransferase 1; Chondroitin 4-sulfotransferase 1; CHST11; IgH/CHST11 fusion
Gene Aliases: C4ST; C4ST-1; C4ST1; CHST11; HSA269537
UniProt ID: (Human) Q9NPF2
Entrez Gene ID: (Human) 50515
Molecular Function: transferase