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CITED1 Antibody (CF807049) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CITED1 (RC202419, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CITED. Positive lysates LY418187 (100 µg) and LC418187 (20 µg) can be purchased separately from OriGene.
Product Details
CF807049
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI3B1
Immunogen
Full length human recombinant protein of human CITED1 produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
This gene encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. The encoded protein, also known as melanocyte-specific gene 1, may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cbp/p300-interacting transactivator 1; Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 1; Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1; melanocyte-specific gene 1; Melanocyte-specific protein 1
Gene Aliases: CITED1; MSG1
UniProt ID: (Human) Q99966
Entrez Gene ID: (Human) 4435
RNA polymerase II transcription coactivator activity
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
protein C-terminus binding
protein homodimerization activity
transcription regulatory region DNA binding
LBD domain binding
co-SMAD binding
transcription cofactor
embryonic axis specification
vasculogenesis
metanephros development
branching involved in ureteric bud morphogenesis
placenta development
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
nucleocytoplasmic transport
apoptotic process
transforming growth factor beta receptor signaling pathway
brain development
cell proliferation
positive regulation of gene expression
negative regulation of Wnt signaling pathway
melanocyte differentiation
positive regulation of transforming growth factor beta receptor signaling pathway
response to lipopolysaccharide
response to insulin
response to cytokine
response to interferon-gamma
pigmentation
negative regulation of neuron apoptotic process
response to estrogen
negative regulation of osteoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to cAMP
mesenchymal to epithelial transition
SMAD protein signal transduction
labyrinthine layer development
spongiotrophoblast layer development
response to interleukin-1
response to interleukin-2
response to interleukin-4
response to interleukin-6
response to interleukin-9
response to interleukin-11
response to parathyroid hormone
response to transforming growth factor beta
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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