Sequence of this protein is as follows: TVSTAVIVFE LTGQIAHILP VMIVVILANA VAQSLQPSLY DSIIRIKKLP YLPELGWGRH QQYRVRVEDI MVRDVPHVAL SCTFRDLRLA LHRTKGRMLA LVESPESMIL LGSIERSQVV ALLGAQLSPA RRRQHMQERR ATQTSPLSDQ EGPPTPEASV CFQVNTEDSA FPAARGETHK PLKPALKRGP SVTRNLGESP TGSAESAGIA LRSLFCGSPP PEAASEKLES CEKRKLKRVR ISLASDADLE GEMSPEETHT IFSLLGVDHA YVTSIGRLIG IVTLKELRKA IEGSVTAQGV KVRPPLASFR DSATSSSDTE TTEVHALWGP HSRHGLPREG SPSDSDDKCQ
The transmembrane protein encoded by this gene is a voltage-gated chloride channel that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: chloride channel 2; Chloride channel protein 2; chloride channel, voltage-sensitive 2; CIC 2; CIC2; ClC-2; EG13
Gene Aliases: CIC-2; clC-2; CLC2; CLCN2; ECA2; ECA3; EGI11; EGI3; EGMA; EJM6; EJM8; LKPAT
UniProt ID: (Human) P51788
Entrez Gene ID: (Human) 1181