Sequence of this protein is as follows: MAEEQPQVEL FVKAGSDGAK IGNCPFSQRL FMVLWLKGVT FNVTTVDTKR RTETVQKLCP GGQLPFLLYG TEVHTDTNKI EEFLEAVLCP PRYPKLAALN PESNTAGLDI FAKFSAYIKN SSPALNDNLE KGLLKALKVL DNYLTSPLPE EVDETSAEDE GVSQRKFLDG NELTLADCNL LPKLHIVQVV CKKYRGFTIP EAFRGVHRYL SNAYAREEFA STCPDDEEIE LAYEQVAKAL K
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
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Protein Aliases: Chloride channel ABP; Chloride intracellular channel protein 1; DADB-110M10.1; FLJ94671; hRNCC; NCC27; Nuclear chloride ion channel 27; nuclear chloride ion channel protein; p64CLCP; Regulatory nuclear chloride ion channel protein; RNCC protein
Gene Aliases: CLIC1; G6; NCC27
UniProt ID: (Human) O00299
Entrez Gene ID: (Human) 1192
Molecular Function: RNA binding protein cytoskeletal protein epimerase/racemase isomerase nucleic acid binding oxidoreductase reductase signaling molecule transferase translation elongation factor translation factor