|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human CNKR2|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CNK homolog protein 2; CNK2; CNK2B; Connector enhancer of kinase suppressor of ras 2; Connector enhancer of KSR 2; connector enhancer of KSR2; KSR2B; Maguin; maguin-1; maguin-2; Membrane-associated guanylate kinase-interacting protein
Gene Aliases: C030004A01; CNK2; CNKSR2; KIAA0902; KSR2; MAGUIN; mKIAA0902
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