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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Chicken / IgY|
|Immunogen||Two peptides from human CNTF which are highly conserved among human and mouse sequences|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-21214 detects CNTF in Human, Mouse and Rat samples.
PA1-21214 has been successfully used in ELISA, Immunohistochemistry and Western Blot procedures.
PA1-21214 immunogen corresponds to Two peptides from human CNTF which are highly conserved among human and mouse sequences.
Ciliary neurotrophic factor (CNTF) is expressed in glial cells within the central and peripheral nervous systems. CNTF stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types such as sensory, sympathetic, ciliary and motor neurons. CNTF itself lacks a classical signal peptide sequence of a secreted protein, but is thought to convey its cytoprotective effects after release from adult glial cells by some mechanism induced by injury. In addition to its neuronal actions, CNTF also acts on non-neuronal cells such as glia, hepatocytes, skeletal muscle, embryonic stem cells and bone marrow stromal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ciliary neurotrophic factor; ciliary neurotropic factor; HCNTF
AI429687; CNTF; HCNTF