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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1180 and 1444 of Human COL3A1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol, 1% BSA|
|Contains||0.025% ProClin 300|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-27828 targets COL3A1 in IHC (P) and WB applications and shows reactivity with Human, Mouse and Rat samples.
The PA5-27828 immunogen is recombinant protein fragment corresponding to a region within amino acids 1180 and 1444 of Human COL3A1.
This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
alpha1 (III) collagen; autosomal dominant; collagen; Collagen alpha-1(III) chain; collagen, fetal; collagen, type III, alpha 1; EDS4A; Ehlers-Danlos syndrome type IV; Ehlers-Danlos syndrome type IV, autosomal dominant; fetal; minisatellite 10w detected by probe MMS10; procollagen, type III, alpha 1
AW550625; Col3a-1; COL3A1; EDS4A; mKIAA4231; MMS10-W; Ms10w