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Product Details
TA505754S
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI2F5
Immunogen
Human recombinant protein fragment corresponding to amino acids 58-327 of human COPS6 produced in E.coli
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Target Information
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: COP9 constitutive photomorphogenic homolog subunit 6; COP9 signalosome complex subunit 6; H_NH0506M12.12; hVIP; JAB1-containing signalosome subunit 6; MOV34 homolog; MOV34 homolog, 34 kD; SGN6; Vpr-interacting protein
Gene Aliases: COPS6; CSN6; HVIP; MOV34-34KD
UniProt ID: (Human) Q7L5N1
Entrez Gene ID: (Human) 10980
Performance Guarantee
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