This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: KWWDEQGVYA PLHSMNDLRV PFIRDNLLKT IPNHQPGKPL LGMKILDVGC GGGLLTEPLG RLGASVIGID PV
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 89%.
Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes. This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2-polyprenyl-6-hydroxyphenol methylase; 2-polyprenyl-6-hydroxyphenyl methylase; 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; 3-demethylubiquinol 3-O-methyltransferase; 3-demethylubiquinone-10 3-methyltransferase; coenzyme Q3 homolog, methyltransferase; coenzyme Q3 methyltransferase; DHHB methyltransferase; DHHB-MT; DHHB-MTase; dihydroxyhexaprenylbenzoate methyltransferase; hexaprenyldihydroxybenzoate methyltransferase, mitochondrial; methyltransferase COQ3; Polyprenyldihydroxybenzoate methyltransferase; Ubiquinone biosynthesis O-methyltransferase, mitochondrial
Gene Aliases: bA9819.1; COQ3; DHHBMT; DHHBMTASE; UG0215E05
UniProt ID: (Human) Q9NZJ6
Entrez Gene ID: (Human) 51805
Molecular Function: methyltransferase