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Product Details
H00010699-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
5B6
Immunogen
CORIN (NP_006578, 616 a.a. approximately 715 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: CKERDLWECP SNKQCLKHTV ICDGFPDCPD YMDEKNCSFC QDDELECANH ACVSRDLWCD GEADCSDSSD EWDCVTLSIN VNSSSFLMVH RAATEHHVCA
Target Information
CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. CORIN converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Atrial natriuretic peptide-converting enzyme; Corin; EC 3.4.21; Heart-specific serine proteinase ATC2; MGC119742; pro-ANP-convertase; Pro-ANP-converting enzyme; PRSC; serine peptidase; serine protease; Transmembrane protease serine 10
Gene Aliases: ATC2; CORIN; CRN; Lrp4; PEE5; TMPRSS10
UniProt ID: (Human) Q9Y5Q5
Entrez Gene ID: (Human) 10699
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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