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Abnova
CORO1C Monoclonal Antibody (1F7)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
H00023603-M02
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1F7
Immunogen
CORO1C (NP_055140, 375 a.a. approximately 473 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: EEWFEGKNAD PILISLKHGY IPGKNRDLKV VKKNILDSKP TANKKCDLIS IPKKTTDTAS VQNEAKLDEI LKEIKSIKDT ICNQDERISK LEQQMAKIA
Target Information
Coronin 3 is associated with the aggression and metastasis of hepatocellular carcinoma. Coronins are a family of highly evolutionary conserved proteins reportedly involved in the regulation of actin cytoskeletal dynamics, although only coronin 3 has been shown to be related to cancer cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: coronin, actin binding protein, 1C; coronin-3; unnamed protein product
Gene Aliases: HCRNN4
UniProt ID: (Human) Q9ULV4
Entrez Gene ID: (Human) 23603
neural crest cell migration
regulation of protein phosphorylation
negative regulation of protein phosphorylation
phagocytosis
actin filament organization
signal transduction
regulation of epithelial cell migration
negative regulation of epithelial cell migration
regulation of fibroblast migration
endosomal transport
negative regulation of protein kinase activity by regulation of protein phosphorylation
establishment of protein localization
positive regulation of osteoclast differentiation
macrophage chemotaxis
negative regulation of cellular component organization
regulation of focal adhesion assembly
negative regulation of focal adhesion assembly
membrane fission
activation of GTPase activity
endosome membrane tubulation
endosome fission
regulation of substrate adhesion-dependent cell spreading
negative regulation of substrate adhesion-dependent cell spreading
regulation of ruffle assembly
positive regulation of lamellipodium morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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