|Tested species reactivity||Chicken, Mouse, Sheep, Rat|
|Published species reactivity||Rabbit|
|Host / Isotype||Goat / IgG|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 1 publications below|
Predicted to react with all mammals based on sequence homology.
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
HGF mediates the anti-inflammatory effects of PRP on injured tendons.
PA1-85118 was used in immunocytochemistry, immunohistochemistry, and western blot to study the role of HGF as the component of platelet-rich plasma that mediates anti-inflammatory activity against injured tendons
|Zhang J,Middleton KK,Fu FH,Im HJ,Wang JH||PloS one (8:null)||2013|