|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthesized peptide derived from N-terminal of human COX17.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
The antibody detects endogenous levels of total COX17 protein.
Cytochrome c oxidase 17 (COX17) is a nuclear gene encoding an assembly protein necessary for proper COX apoenzyme-dependent mitochondrial respiration. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial genes that encode catalytic subunits and several nuclear genes that encode structural subunits. COX17 influences the recruitment of copper to the mitochondria for incorporation into the COX apoenzyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: COX17; COX17 cytochrome c oxidase assembly homolog; COX17 cytochrome c oxidase copper chaperone; COX17 homolog, cytochrome c oxidase assembly protein; cytochrome c oxidase 17 copper chaperone; cytochrome c oxidase assembly homolog 17; Cytochrome c oxidase copper chaperone; cytochrome c oxidase subunit XVII assembly protein homolog; cytochrome c oxidase, subunit XVII assembly protein homolog; human homolog of yeast mitochondrial copper recruitment
Gene Aliases: AI037035; COX17; Cox17a
Molecular Function: transfer/carrier protein
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