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Cytochrome c oxidase 17 (COX17) is a nuclear gene encoding an assembly protein necessary for proper COX apoenzyme-dependent mitochondrial respiration. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial genes that encode catalytic subunits and several nuclear genes that encode structural subunits. COX17 influences the recruitment of copper to the mitochondria for incorporation into the COX apoenzyme.
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Protein Aliases: COX17 cytochrome c oxidase assembly homolog; COX17 cytochrome c oxidase copper chaperone; cytochrome c oxidase 17 copper chaperone; cytochrome c oxidase assembly homolog 17; Cytochrome c oxidase copper chaperone; human homolog of yeast mitochondrial copper recruitment
Gene Aliases: COX17
UniProt ID: (Human) Q14061
Entrez Gene ID: (Human) 10063
Molecular Function: chaperone