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Product Details
PA5-99810
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human COX6B2(Accession Q6YFQ2), corresponding to amino acid residues M1-R41.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2818743
Product Specific Information
Antibody detects endogenous levels of total COX6B2.
Target Information
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Localized to the intermembrane space, COX6b2 (Cytochrome c oxidase subunit 6B2), also known as Cytochrome c oxidase subunit VIb isoform 2 and Cancer/testis antigen 59, is a 88 amino acid mitochondrial protein that is responsible for joining the two COX monomers to form the COX dimer. COX6b2 is specifically expressed in testis and is found to be upregulated in certain cancer cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cancer/testis antigen 59; COX VIb-2; CT59; Cytochrome c oxidase subunit 6B2; Cytochrome c oxidase subunit VIb isoform 2; cytochrome c oxidase subunit VIb polypeptide 2 (testis); cytochrome c oxidase subunit VIb, testes-specific; Cytochrome c oxidase subunit VIb, testis-specific isoform
Gene Aliases: 1700067P11Rik; BC048670; COX6B2; COXVIB2; CT59
UniProt ID: (Human) Q6YFQ2, (Mouse) Q80ZN9
Entrez Gene ID: (Human) 125965, (Mouse) 333182
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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