Sequence of this protein is as follows: MYYKFSGFTQ KLAGAWASEA YSPQGLKPVV STEAPPIIFA TPTKLTSDST VYDYAGKNKV PELQKFFQKA DGVPVYLKRG LPDQMLYRTT MALTVGGTIY CLIALYMASQ PKNK
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX7a2 (cytochrome c oxidase subunit VIIa polypeptide 2), also known as COX7AL or COX7AL1, is an 83 amino acid protein that localizes to the inner mitochondrial membrane and exists as a component of the COX complex, playing an important role in electron transport. COX7a2L (cytochrome c oxidase subunit 7A-related protein), also known as COX7AR or COX7RP, is an inner mitochondrial membrane protein that consists of 114 amino acids and is induced by estrogen.
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Protein Aliases: COX7a-related protein; Cytochrome c oxidase subunit 7A-related protein, mitochondrial; cytochrome c oxidase subunit VII-related protein; cytochrome c oxidase subunit VIIa polypeptide 2 like; Cytochrome c oxidase subunit VIIa-related protein; EB1; estrogen receptor binding CpG island
Gene Aliases: COX7A2L; COX7AR; COX7RP; EB1; SIG81
UniProt ID: (Human) O14548
Entrez Gene ID: (Human) 9167