This antibody is predicted to react with Monkey, Dog, Pig, Rabbit.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Corticotropin-releasing hormone receptor 1 (CRHR1) is a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants, one of which is a non-coding read-through transcript with the neighboring gene MGC57346.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: corticotrophin releasing hormone receptor 1; corticotropin releasing hormone 1; Corticotropin-releasing factor receptor 1; corticotropin-releasing factor type 1 receptor; Corticotropin-releasing hormone receptor 1; CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR; CRFR-1; CRH receptor 1; CRH-R 1; CRH-R-1; CRH-R1; seven transmembrane helix receptor; CRFR1; CRHR
Gene Aliases: CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRHR; CRHR1; CRHR1L