|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 15 amino acid peptide from N-terminal extracellular domain of human CRF1.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Hamster, Panda, Horse (100%).
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants one of which is a non-coding read-through transcript with the neighboring gene MGC57346.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: corticotropin releasing hormone receptor variant 1e; corticotropin releasing hormone receptor variant 1g; corticotropin-releasing factor receptor 1; corticotropin-releasing factor type 1 receptor; corticotropin-releasing hormone receptor 1; CRF-R; CRF-R1; CRFR-1; CRFR1; CRH receptor 1; CRH-R1; CRH-R1h; CRHR; CRHR1f; CRHR1L; seven transmembrane; seven transmembrane helix receptor
Gene Aliases: CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRHR; CRHR1L
Entrez Gene ID: (Human) 1394
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