Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating the stress response and anxiety-related behaviors. Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease. Multiple isoforms of CRFR1 are produced by alternative splicing. CRFR1 has been reported to be expressed in the pituitary, adrenal gland, brain, colon, ovary, placenta, testis, white blood cells, and skin. ESTs have been isolated from human brain, eye, colon, and embryo libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: corticotrophin releasing hormone receptor 1; corticotropin releasing hormone 1; Corticotropin-releasing factor receptor 1; Corticotropin-Releasing Factor Receptor 1 (extracellular); corticotropin-releasing factor type 1 receptor; Corticotropin-releasing hormone receptor 1; CRF 1 receptor; CRF-R; CRF-R-1; CRF-R1; CRF-R1alpha; CRF1; CRFR-1; CRH receptor 1; CRH receptor subtype-1 isoform-3; CRH-R 1; CRH-R-1; CRH-R1; seven transmembrane helix receptor
Gene Aliases: CRF-R; CRF-R-1; CRF-R1; CRF1; CRFR; CRFR-1; CRFR1; CRH-R-1; CRH-R1; CRHR; CRHR1; CRHR1L