This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Product may be stored at -20C for one year. After reconstitution, at 4C for one month. Product can also be aliquotted and stored frozen at -20C for a longer time. Avoid repeated freezing and thawing.
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
MA5-27879 has been validated to detect CRM1 in rat, mouse, human and canine.
The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chromosome region maintenance 1 homolog; Chromosome region maintenance 1 protein homolog; CRM1; Exp1; exportin 1 (CRM1 homolog, yeast); exportin 1 (CRM1, yeast, homolog); exportin 1, CRM1 homolog; Exportin-1; exportin-1 (required for chromosome region maintenance); XPO1
Gene Aliases: AA420417; CRM1; emb; Exp1; XPO1
Molecular Function: receptor