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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 20 amino acid peptide from C-terminal cytoplasmic domain of human GPR44 / CRTH2.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||15 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Pig (85%) Elephant (80%).
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthama susceptibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD294; chemoattractant receptor homologous molecule expressed on T helper type 2 cells; Chemoattractant receptor-homologous molecule expressed on Th2 cells; CRTH2; DL1R; DP2; G Protein-Coupled Rec. 44; G protein-coupled receptor 44; G-protein coupled receptor 44; GPR44; Prostaglandin D2 receptor 2; putative G-protein coupled receptor 44
CD294; CRTH2; DL1R; DP2; GPR44; PTGDR2