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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CSAG2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The expression of the cancer-testis antigen Taxol resistanceassociated gene-3 (TRAG-3) is associated with acquired paclitaxel (Taxol) resistance, and is expressed in a variety of cancers - e.g., breast cancer, leukemia, and melanoma. Overexpressed in taxolresistant breast cancer line MDA 435(TR) and the doxorubicinresistant multiple myelanoma lines 8226/Dox(40) and 8226/MDR (10)V. Weakly expressed in kidney. TRAG-3 is an attractive target for immunotherapy of cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Cancer/testis antigen 24.2; cancer/testis antigen family 24; Chondrosarcoma-associated gene 2/3 protein; CSAG family; CSAG family, member 3A; CSAG3; CSAG3B; CT24.2; member 2; member 3B; taxol resistance associated gene 3; Taxol-resistant-associated gene 3 protein; TRAG-3; TRAG3
CSAG2; CSAG3; CSAG3A; CT24.2; TRAG3