In direct ELISAs, no cross-reactivity with recombinant human (rh) GM-CSF R alpha orrhGM-CSF R beta is observed.
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.
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Protein Aliases: CD116; colony stimulating factor 2 receptor alpha chain; CSF 2R; GM CSF R alpha; GM-CSF-R-alpha; GM-CSFRalpha; GMCSFR-alpha; GMR-alpha; Granulocyte-macrophage colony-stimulating factor receptor subunit alpha; MGC3848; MGC4838
Gene Aliases: CD116; Csf2ra; Csfgmra; GM-CSF-Ra; GM-CSFR
UniProt ID: (Mouse) Q00941
Entrez Gene ID: (Mouse) 12982
Molecular Function: transmembrane signal receptor