|Tested species reactivity||Mouse, Rat|
|Published species reactivity||Yeast, Not Applicable|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Purified, recombinant, human CSPS protein expressed in E. coli.|
|Purification||Ammonium sulfate precipitation|
|Storage buffer||HEPES with 0.15M NaCl, 0.01% BSA, 50% glycerol|
|Contains||0.03% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunoprecipitation (IP)||1-2 µl|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control for this product is mouse brain.
The human Catecholamine-Sulfating Phenol Sulfotransferase (CSPS) is the only sulfotransferase that catalyzes the sulfation of catecholamins, in particular the neurotransmitter dopamine, with high activity. CSPS is required for stimulation by Mn2+ of the sulfating activity and expressed in the human intestine, brain, platelet and other tissues. In the brain it may play a role in regulating the levels of dopamine. It also serves as a detoxifying function in the intestine, where it may detoxify potentially lethal dietary monoamines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Structure-based analyses reveal distinct binding sites for Atg2 and phosphoinositides in Atg18.
LF-MA0078 was used in western blot to identify the binding sites for Atg2 and phosphoinositides in Atg18
|Watanabe Y,Kobayashi T,Yamamoto H,Hoshida H,Akada R,Inagaki F,Ohsumi Y,Noda NN||The Journal of biological chemistry (287:31681)||2012|
|Not Applicable||Not Cited||
Method for targeting protein destruction by using a ubiquitin-independent, proteasome-mediated degradation pathway.
LF-MA0078 was used in immunoprecipitation to utilize a ubiquitin-independent, proteasome-mediated degradation pathway as a method for targeting protein destruction
|Matsuzawa S,Cuddy M,Fukushima T,Reed JC||Proceedings of the National Academy of Sciences of the United States of America (102:14982)||2005|