Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1-5 µg/mL | - |
ELISA (ELISA) |
0.3 ng/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Mouse / IgG2a, kappa |
Class |
Monoclonal |
Type |
Antibody |
Clone |
5G6 |
Immunogen |
CTNS (NP_004928, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
See Label |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4 |
Contains |
no preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Sequence of this protein is as follows: MIRNWLTIFI LFPLKLVEKC ESSVSLTVPP VVKLENGSST NVSLTLRPPL NATLVITFEI TFRSKNITIL ELPDEVVVPP GVTNSSFQVT SQNVGQLTVY
This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes. Its activity is driven by the H+ electrochemical gradient of the lysosomal membrane. Mutations in this gene cause cystinosis, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cystinosin; cystinosis nephropathic; cystinosis, nephropathic
Gene Aliases: AI195360; AW049661; CTNS; CTNS-LSB; PQLC4
UniProt ID: (Human) O60931, (Mouse) P57757
Entrez Gene ID: (Human) 1497, (Mouse) 83429, (Rat) 287478
Molecular Function:
amino acid transporter
transporter
secondary carrier transporter
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