|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 250-278 amino acids from the central region of human CUL4B|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with mouse based on sequence homology.
This gene is a member of the cullin family. The encodedprotein forms a complex that functions as an E3 ubiquitin ligaseand catalyzes the polyubiquitination of specific protein substratesin the cell. The protein interacts with a ring finger protein, andis required for the proteolysis of several regulators of DNAreplication including chromatin licensing and DNA replicationfactor 1 and cyclin E. Multiple transcript variants encodingdifferent isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.