Intact IgG appears on a non-reducing gel as ~150 kDa band and upon reduction generating a ~25 kDa light chain band and a ~50 kDa heavy chain.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Macrophage inflammatory protein 2 is a chemokine involved in the pulmonary inflammatory response. MIP-2 is produced by activated monocytes and neutrophils and expressed at sites of inflammation. In vitro, it suppresses hematopoietic progenitor cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-X-C motif chemokine 2; CINC-2a; CINC-3; Cytokine-induced neutrophil chemoattractant 3; Gro2; GROb; Macrophage inflammatory protein 2; Mgsa-b; MIP-2a; MIP2; Scyb; Scyb2; small inducible cytokine subfamily, member 2
Gene Aliases: CINC-2a; Cinc3; Cxcl2; Gro2; GROb; Mgsa-b; MIP-2; MIP-2a; Mip2; Scyb; Scyb2