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|Tested species reactivity||Human|
|Published species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant human IL-8.|
|Storage buffer||PBS, pH 7.5|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|ELISA (ELISA)||See 4 publications below|
This product is recommended as a capture antibody in Sandwich ELISA applications.
Interleukin 8 is a pro-inflammatory factor which belongs to the CXC subfamily of chemokinesk, and which are bound by the cell surface receptors IL-8RA and IL-8RB. IL-8 functions as a chemoattractant and is a potent angiogenic factor. The expression and secretion of IL-8 can be induced by diverse inflammatory stimuli in many cells, including macrophages and endothelial cells. In endothelial cells, IL-8 is present in storage vesicles called Weibel-Palade bodies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
IL-8 and cathepsin B as melanoma serum biomarkers.
AHC0982 was used in ELISA to study IL8 and Cathepsin B in the prognosis of melanoma mortality.
|Zhang H,Fu T,McGettigan S,Kumar S,Liu S,Speicher D,Schuchter L,Xu X||International journal of molecular sciences (12:1505)||2011|
|Mouse||Not Cited||Biological characterization of lipopolysaccharide from Treponema pectinovorum.||Kesavalu L,Falk CW,Davis KJ,Steffen MJ,Xu X,Holt SC,Ebersole JL||Infection and immunity (70:211)||2002|
|Human||Not Cited||Parathyroid hormone-related protein induces interleukin 8 production by prostate cancer cells via a novel intracrine mechanism not mediated by its classical nuclear localization sequence.||Gujral A,Burton DW,Terkeltaub R,Deftos LJ||Cancer research (61:2282)||2001|
|Human||Not Cited||Cytokine responses to treponema pectinovorum and treponema denticola in human gingival fibroblasts.||Nixon CS,Steffen MJ,Ebersole JL||Infection and immunity (68:5284)||2000|
alveolar macrophage chemotactic factor I; beta endothelial cell-derived neutrophil activating peptide; beta-thromboglobulin-like protein; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; CXCL8; Emoctakin; GCP-1; GCP1; Granulocyte chemotactic protein 1; IL-8; interleukin 8; Interleukin-8; LECT; LUCT; lung giant cell carcinoma-derived chemotactic protein; lymphocyte derived neutrophil activating peptide; LYNAP; MDNCF; MONAP; Monocyte-derived neutrophil chemotactic factor; Monocyte-derived neutrophil-activating peptide; NAF; NAP-1; neutrophil-activating peptide 1; Neutrophil-activating protein 1; Protein 3-10C; small inducible cytokine subfamily B, member 8; T-cell chemotactic factor; tumor necrosis factor-induced gene 1
CXCL8; GCP-1; GCP1; IL8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1