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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2b, kappa|
|Immunogen||Human CD181 Protein|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
IL8RA, IL8RBA, C-C-CKR-1, IL8R1, CMKAR1, CDw128a, C-C, CD128, CKR-1, CD181
C-X-C chemokine receptor type 1, CXC-R1, CXCR-1, IL-8 receptor type 1, IL-8R A, high affinity interleukin-8 receptor A, interleukin 8 receptor, alpha, interleukin-8 receptor type 1, interleukin-8 receptor type A, C-C, C-C-CKR-1, CD128, CD181, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA, IL-8 Receptor alpha, IL-RA