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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (aa sequence is considered to be commercially sensitive)|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.7|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-20673 detects CXCR2 in Human samples.
PA1-20673 has been successfully used in Immunohistochemistry (Paraffin) procedures.
PA1-20673 immunogen corresponds to Synthetic peptide (aa sequence is considered to be commercially sensitive).
CXCR2 is a receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to GRO/MGSA and NAP-2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD182; CD182 antigen; chemokine (C-X-C motif) receptor 2; chemokine (CXC) receptor 2; CMKAR2; CXC-R2; CXCR-2; CXCR2; CXCR2 gene for IL8 receptor type B; GRO/MGSA receptor; high affinity interleukin-8 receptor B; Il-8 receptor b; IL-8 receptor beta; IL-8 receptor type 2; IL-8R B; Il-8rb; IL8R2; IL8RB; interleukin 8 receptor B; interleukin 8 receptor type 2; interleukin 8 receptor, beta; interleukin-8 receptor type B
CD182; CDw128b; CMKAR2; CXCR2; IL8R2; IL8RA; IL8RB