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CYP26B1 Antibody (CF811497) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP26B1 (SC120°C99, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP2. Positive lysates LY402746 (100 µg) and LC402746 (20 µg) can be purchased separately from OriGene.
Product Details
CF811497
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI4A8
Immunogen
Human recombinant protein fragment corresponding to amino acids 229-512 of human CYP26B1 produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene is involved in the specific inactivation of all-trans-retinoic acid to hydroxylated forms, such as 4-oxo-, 4-OH-, and 18-OH-all-trans-retinoic acid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytochrome P450 26A2; Cytochrome P450 26B1; cytochrome P450 family 26 subfamily A member 1; Cytochrome P450 retinoic acid-inactivating 2; cytochrome P450 retinoid metabolizing protein; cytochrome P450, 26, retinoic acid B1; cytochrome P450, family 26, subfamily B, polypeptide 1; cytochrome P450, subfamily XXVIB, polypeptide 1; Cytochrome P450RAI-2; P450 26A2; retinoic acid B1; retinoic acid hydroxylase; Retinoic acid-metabolizing cytochrome
Gene Aliases: CP26; CYP26A2; CYP26B1; P450RAI-2; P450RAI2; RHFCA
UniProt ID: (Human) B7Z2K6, (Mouse) Q811W2, (Rat) G3V7X8
Entrez Gene ID: (Human) 56603, (Mouse) 232174, (Rat) 312495
retinoic acid binding
iron ion binding
retinoic acid 4-hydroxylase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
heme binding
monooxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
fluorene oxygenase activity
mono-butyltin dioxygenase activity
tri-n-butyltin dioxygenase activity
di-n-butyltin dioxygenase activity
methylsilanetriol hydroxylase activity
methyl tertiary butyl ether 3-monooxygenase activity
4-nitrocatechol 4-monooxygenase activity
4-chlorophenoxyacetate monooxygenase activity
tert-butanol 2-monooxygenase activity
alpha-pinene monooxygenase activity
dimethylsilanediol hydroxylase activity
ammonia monooxygenase activity
hydroxymethylsilanetriol oxidase activity
2-hydroxyisobutyrate 3-monooxygenase activity
alpha-pinene dehydrogenase activity
bisphenol A hydroxylase B activity
2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity
9-fluorenone-3,4-dioxygenase activity
anthracene 9,10-dioxygenase activity
2-(methylthio)benzothiazole monooxygenase activity
2-hydroxybenzothiazole monooxygenase activity
benzothiazole monooxygenase activity
2,6-dihydroxybenzothiazole monooxygenase activity
pinacolone 5-monooxygenase activity
thioacetamide S-oxygenase activity
thioacetamide S-oxide S-oxygenase activity
endosulfan monooxygenase I activity
N-nitrodimethylamine hydroxylase activity
4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity
endosulfan ether monooxygenase activity
pyrene 4,5-monooxygenase activity
pyrene 1,2-monooxygenase activity
1-hydroxypyrene 6,7-monooxygenase activity
1-hydroxypyrene 7,8-monooxygenase activity
phenylboronic acid monooxygenase activity
spheroidene monooxygenase activity
metal ion binding
oxygenase
cell fate determination
establishment of T cell polarity
vitamin metabolic process
xenobiotic metabolic process
inflammatory response
male meiosis
spermatogenesis
proximal/distal pattern formation
positive regulation of gene expression
embryonic limb morphogenesis
retinoic acid catabolic process
tongue morphogenesis
regulation of T cell differentiation
retinoic acid receptor signaling pathway
negative regulation of retinoic acid receptor signaling pathway
oxidation-reduction process
bone morphogenesis
establishment of skin barrier
cornification
cellular response to retinoic acid
positive regulation of tongue muscle cell differentiation
retinoic acid metabolic process
regulation of retinoic acid receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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