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Invitrogen
Calbindin D28K Monoclonal Antibody (CB-955)
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FIGURE: 1 / 7
Calbindin D28K Antibody (MA5-32993) in IHC (P)
Immunohistochemical analysis of Calbindin-D in paraffin-embedded section of mouse brain tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution ) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1μg/mL mouse anti-Calbindin-D antibody (Product # MA5-32993) overnight at 4°C. DyLight®488 Conjugated Goat... View More
Product Details
MA5-32993
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
CB-955
Immunogen
Bovine kidney calbindin-D.
Conjugate
Form
Lyophilized
Concentration
100 µg/mL
Storage buffer
ascites/1.2% sodium acetate with 2mg BSA
Contains
0.01mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 1 mL of PBS buffer to yield a concentration of 100 µg/mL.
Positive Control - WB: Rat Brain Tissue, Rat Brain Tissue, Rat Kidney Tissue, Rat Lung Tissue, rat brain tissue, rat kidney tissue, mouse brain tissue. IHC: Mouse Kidney Tissue, Human Intestinal Cancer Tissue, Rat Kidney Tissue, Human Mammary Cancer Tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin), is a highly conserved 28kDa calcium binding protein, with broad tissue distribution. It belongs, together with calmodulin, S-100, parvalbumin, troponin C and other proteins, to a family of low molecular weight calcium-binding proteins (CaBPs). These CaBPs have homologous primary structures, which contain conserved polypeptide folds of the EF-hand type for Ca2+ binding. Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons, and in certain epithelial nervous system neurons, and in certain epithelial cells involved in Ca2+ transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calbindin; calbindin 1, (28kD); calbindin 1, 28 kD; calbindin 1, 28kDa; calbindin 27; Calbindin D28; calbindin-28K; calbindin-D (28k); calbindin-D28k; CalbindinD28K; cerebellar Ca-binding protein spot 35 protein; cerebellar Ca-binding protein, spot 35 protein; D-28K; PCD-29; retrovirus-like H primer binding sequence protein; RTVL-H protein; Spot 35 protein; unnamed protein product; Vitamin D-dependent calcium-binding protein, avian-type
Gene Aliases: Brain-2; CAB27; CaBP28K; CALB; Calb-1; CALB1; CB; D-28K
UniProt ID: (Bovine) P04467, (Human) P05937, (Rat) P07171, (Mouse) P12658
Entrez Gene ID: (Bovine) 539930, (Human) 793, (Rat) 83839, (Mouse) 12307
short-term memory
long-term memory
locomotory behavior
retina layer formation
metanephric part of ureteric bud development
cellular response to organic substance
metanephric collecting duct development
metanephric distal convoluted tubule development
metanephric connecting tubule development
regulation of postsynaptic cytosolic calcium ion concentration
learning or memory
response to auditory stimulus
regulation of synaptic plasticity
calcium ion homeostasis
retina development in camera-type eye
cochlea development
regulation of presynaptic cytosolic calcium ion concentration
vitamin D metabolic process
regulation of cytosolic calcium ion concentration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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