|Tested species reactivity||Fish|
|Host / Isotype||Mouse / IgG|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||20 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA3-021A detects calcitonin (CT) from salmon tissues. This antibody cross reacts with glycine-extended salmon calcitonin, but is unreactive with salmon calcitonin peptides 23-30 and 26-32. It shows no cross reactivity with human calcitonin.
MA3-021A has been successfully used in ELISA procedures. By ELISA this antibody is useful in solid-phase or competitive solution based procedures with a sensitivity of approximately 50 ng/ml.
The MA3-021A antigen is salmon calcitonin. This antibody was raised against salmon calcitonin which, as in the naturally occurring peptide, contains a C-terminal prolinamide. The epitope recognized likely lies in the N-terminal portion of the molecule.
Reconstitute with PBS.
Calcitonin (CT) is a polypeptide hormone known to act primarily on bone, and to have effects on the renal and gastrointestinal systems. It is secreted by the ultimobranchial gland of birds and fish, and by the thyroid gland in mammals. Salmon CT is used therapeutically to inhibit bone resorption, particularly in patients with Paget's disease and osteoporosis. Salmon CT appears to have essentially the same actions as mammalian CT, but has shown to have greater potency and longer lasting effects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.