|Flow Cytometry (Flow)||1 µg/10^6 cells|
|Immunohistochemistry (Frozen) (IHC (F))||1:50-1:200|
|Western Blot (WB)||1:50-1:200|
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
|Tested Species reactivity||Human, Mouse, Rabbit, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||N-terminal extracellular region of the human Calcium Sensing Receptor .|
|Storage buffer||tris glycine with 0.15M NaCl|
|Contains||0.05% sodium azide|
|Storage conditions||-20°C or -80°C if preferred|
Suggested positive control: antigen standard for CASR (transient overexpression lysate), human kidney protein.
The calcium-sensing receptor (CaSR) is an integral membrane protein that is a member of the G protein-coupled receptor family. It senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: calcium-sensing receptor; Calcium-sensing receptor (hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism); Calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism); CaR; CaSR; CaSR antibody; cation sensing receptor; Extracellular calcium-sensing receptor; G protein coupled receptor, family C, group 2, member A; G protein-coupled receptor, family C, group 2, member A; parathyroid Ca(2+)-sensing receptor 1; Parathyroid cell calcium-sensing receptor; Parathyroid cell calcium-sensing receptor 1; Parathyroid Cell calcium-sensing receptor antibody.; PCaR1
Gene Aliases: CAR; CASR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1
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