This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
MA5-11620 targets Calponin-1 in IHC (P) applications and shows reactivity with Human and Rat samples.
The MA5-11620 immunogen is crude human uterus extract.
Calponin, a calmodulin, binds tropomyosin and F-actin and is thought to be involved in the regulation of smooth muscle contraction. The expression of calponin is restricted to smooth muscle cells and is a marker of the differentiated contractile phenotype of developing smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: basic; Basic calponin; calponin 1, basic, smooth muscle; calponin 1, smooth muscle; calponin H1; Calponin H1, smooth muscle; Calponin-1; calponins; calponins, basic; epididymis secretory protein Li 14; smooth muscle
Gene Aliases: CN; CNN1; CnnI; HEL-S-14; Sm-Calp; SMCC