MA5-14540 targets Calretinin in WB and IHC (P) applications and shows reactivity with Human and Mouse samples.
The MA5-14540 immunogen is recombinant full-length mouse calretinin protein.
Calretinin is an intracellular calcium-binding protein belonging to the troponin C superfamily characterized by a structural motif described as the EF-hand domain. The immunohistochemical detection of calretinin in developing cerebellum is restricted to the later stages indicated by weak staining from week 21 of gestation, in Purkinje and basket cells and in neurons of the dentate nucleus. The intensity of staining increases as the cerebellum matures. In tumors, calretinin has been detected in mesotheliomas and some pulmonary adenocarcinomas.
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Protein Aliases: (29kD; 29 kDa calbindin; calbindin 2; calbindin 2, (29kD, calretinin); calbindin D29K; Calretinin; calretinin); CR; testicular secretory protein Li 8
Gene Aliases: CAB29; CAL2; CALB2; CR
Molecular Function: calcium-binding protein