|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Full length native protein (purified from Human Erythrocytes) (Human).|
|Storage buffer||PBS, pH 7.2, with 40% glycerol|
|Contains||0.01% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-28951 detects Carbonic Anhydrase I from human samples.
PA1-28951 has been successfully used in ELISA applications.
The PA1-28951 immunogen is: Full length native protein (purified from Human Erythrocytes) (Human).
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.