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Invitrogen
Carbonic Anhydrase II Recombinant Rabbit Monoclonal Antibody (2)
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 2
Carbonic Anhydrase II Antibody (MA5-30206) in WB
Western blot was performed using Anti-Carbonic Anhydrase II Monoclonal Antibody (Product # MA5-30206) and a ~30kDa band corresponding to CA2 was observed across tissues tested except in Mouse Skeletal muscle which is reported to be negative. Tissue extracts (30 µg lysate) of Mouse Colon (Lane 1), Rat Colon (Lane 2), Mouse Kidney (Lane 3) and Mouse Skeletal muscle (Lane 4) were electrophoresed using NuPAGE® ... View More
Product Details
MA5-30206
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
2
Immunogen
Recombinant Mouse Carbonic Anhydrase II/CA2 protein (Met1-Lys260)
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
RRID
AB_2785968
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Mouse Carbonic Anhydrase II/CA2.
Target Information
CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CA II; CA-II; Carbonate dehydratase II; Carbonic anhydrase 2; Carbonic anhydrase II
Gene Aliases: AI131712; Ca2; CAII; Car-2; Car2; Ltw-5; Lvtw-5
UniProt ID: (Mouse) P00920
Entrez Gene ID: (Mouse) 12349
morphogenesis of an epithelium
one-carbon metabolic process
regulation of pH
carbon dioxide transport
positive regulation of synaptic transmission, GABAergic
positive regulation of cellular pH reduction
angiotensin-activated signaling pathway
regulation of anion transport
positive regulation of osteoclast differentiation
positive regulation of bone resorption
secretion
regulation of intracellular pH
positive regulation of dipeptide transmembrane transport
regulation of chloride transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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