Invitrogen
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
0.25-12.5 µg/mL | - |
Immunohistochemistry (IHC) |
- | View 1 publication 1 publication |
Immunohistochemistry (Frozen) (IHC (F)) |
5-15 µg/mL | - |
Immunoprecipitation (IP) |
25 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Mouse |
Published species |
Not Applicable |
Host/Isotype |
Goat / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Mouse myeloma cell line NS0-derived recombinant mouse Carbonic Anhydrase IV/CA4 Glu18-Ser277 |
Conjugate |
Unconjugated |
Form |
Lyophilized |
Concentration |
0.2 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS with 5% trehalose |
Contains |
No Preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2607329 |
In direct ELISAs and Western blots, approximately 15% cross-reactivity with recombinant human (rh) CA4 is observed and less than 2% cross-reactivity with rhCA3, rhCA10, rhCA13, recombinant mouse (rm) CA9, and rmCA12 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary capillaries and proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CA IV; CA-IV; Carbonate dehydratase IV; Carbonic anhydrase 4; Carbonic anhydrase IV
Gene Aliases: AW456718; Ca4; Car4
UniProt ID: (Mouse) Q64444
Entrez Gene ID: (Mouse) 12351
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