This Antibody was verified by Cell Treatment to ensure that the antibody binds to the antigen stated. View Details
MA5-15737 targets CA9 in FACS, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15737 immunogen is purified recombinant fragment of human CA9 expressed in E. Coli.
MA5-15737 detects CA9 which has a predicted molecular weight of approximately 50kDa.
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CA-IX; CA9; CAIX; Carbonate dehydratase IX; Carbonic anhydrase 9; Carbonic anhydrase IX; carbonic dehydratase; Membrane antigen MN; MN; P54/58N; pMW1; RCC-associated antigen G250; RCC-associated protein G250; Renal cell carcinoma-associated antigen G250
Gene Aliases: CA9; CAIX; G250; MN
UniProt ID: (Human) Q16790
Entrez Gene ID: (Human) 768