Recommended positive controls: A549, HeLa.
Predicted reactivity: Zebrafish (83%), Rhesus Monkey (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.
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Protein Aliases: CA-related protein; CA-VIII; carbonate dehydratase; Carbonic anhydrase VIII; carbonic anhydrase-like sequence; Carbonic anhydrase-related protein; CARP; MGC120502; MGC99509
Gene Aliases: CA-RP; CA-VIII; CA8; CALS; CAMRQ3; CARP
UniProt ID: (Human) P35219
Entrez Gene ID: (Human) 767