In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant mouse CA14 is observed and less than 1% cross-reactivity with recombinant human CA1, 2, 3, 4, 8, 9, 10, 12, and 13 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
CA14 belongs a large family of zinc metalloenzymes that catalyze the versible hydration of carbon dioxide. The protein is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles.
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Protein Aliases: CA-XIV; Carbonate dehydratase XIV; Carbonic anhydrase 14; Carbonic anhydrase XIV; carbonic dehydratase
Gene Aliases: CA14; CAXiV; UNQ690/PRO1335
UniProt ID: (Human) Q9ULX7
Entrez Gene ID: (Human) 23632