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In direct ELISAs and Western blots, approximately 30% cross-reactivity with recombinant human (rh) CA14 is observed and less than 5% cross-reactivity with rhCA1, -2, -3, -6, -8, -10, -13, recombinant mouse CA4, -9, and -12 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
CA14 belongs a large family of zinc metalloenzymes that catalyze the versible hydration of carbon dioxide. The protein is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CA XIV; CA-XIV; Carbonate dehydratase XIV; Carbonic anhydrase 14; Carbonic anhydrase XIV; carbonic dehydratase
Gene Aliases: AW536446; CA14; Car14; Catm; CAXiV; UNQ690/PRO1335
UniProt ID: (Human) Q9ULX7, (Mouse) Q9WVT6
Entrez Gene ID: (Human) 23632, (Rat) 791259, (Mouse) 23831
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