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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 143 and 388 of Human Carboxypeptidase E|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:10,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28376 targets Carboxypeptidase E in WB applications and shows reactivity with Human and mouse samples.
The PA5-28376 immunogen is recombinant fragment corresponding to a region within amino acids 143 and 388 of Human Carboxypeptidase E.
This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
carboxypeptidase E; carboxypeptidase H; cobalt-stimulated chromaffin granule carboxypeptidase; CPH; enkephalin convertase; insulin granule-associated carboxypeptidase; prohormone-processing carboxypeptidase
CPE; CPH; Cph-1; Cph1; fat; R74677