Immunogen sequence: VQATGALYSR SLTPDDDVFQ YLAHTYASRN PNMKKGDECK NKMNFPNGVT NGYSWYPLQG GMQDYNYIWA QCFEITLELS CCKYPREEKL PSFWNNNKAS LIEYIKQVHL GVKGQVFDQN GNPLPNVIVE VQDRKHICPY RTNKYGEYYL LLLPGSYIIN VTVPGHDPHI TKVIIPEKSQ NFSALKKDIL LPFQGQLDSI PVSNPSCPMI PLYRNLPDHS AATKPSLFLF LVSLLHIFFK; Positive Samples: HeLa; Cellular Location: Cell membrane, GPI-anchor, Lipid-anchor
The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.
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Protein Aliases: Carboxypeptidase M; CPM; renal carboxypeptidase; urinary carboxypeptidase B
Gene Aliases: CPM
UniProt ID: (Human) P14384
Entrez Gene ID: (Human) 1368